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About 3.8 million people in the United States — four times the number two years ago — are now taking the most popular weight-loss drugs, according to the IQVIA Institute for Human Data Science, an industry data provider.Some of these prescriptions are for diabetes. The medicines are Novo Nordisk’s Ozempic and Wegovy (the same drug sold under different brand names), and Eli Lilly’s Mounjaro and Zepbound (also the same drug).Pent-up demand is even higher, because many people who want the drugs cannot find or afford them. Without insurance coverage, people have to pay out of their own pockets. If they…

Why It Matters: The price offers kick off negotiations.The medicines selected for negotiations are taken by millions of Americans to treat conditions like diabetes, cancer and heart disease. The administration identified them in August, beginning a lengthy process intended to result in an agreed-upon price that would take effect in 2026, assuming the negotiation program survives legal challenges.The initial round of price offers is a key step in the negotiation process. Each drugmaker has until early March to accept the offer or propose a counteroffer to the government. A series of negotiation sessions could follow, with the process set to…

Why It Matters: Penguins are already under pressure.The familiar black-and-white birds are facing numerous threats, including climate change, pollution and commercial fishing. Three Antarctic penguin species — emperor penguins, southern rockhopper penguins and macaroni penguins — are listed as vulnerable or near threatened.Before H5N1 arrived in the Antarctic region last fall, highly pathogenic bird flu viruses had never been documented in the area before. That means that the penguins are likely to have little existing immunity. And because they breed in large, crowded colonies, once one penguin is infected, the virus could spread rapidly, causing mass mortalities. (As the virus…